Preheat oven to 350°F. Grease a 7-inch springform pan and line with parchment.
Combine crushed gluten-free graham crackers, 2 tbsp powdered sugar, and melted butter. Press into the prepared pan.
Bake crust for 10 minutes until lightly golden. Let cool.
Beat cream cheese, lemon zest, and ¾ cup powdered sugar until fluffy. Add eggs one at a time, mixing well.
Stir in sour cream, lemon juice, and gluten-free vanilla extract until smooth.
Pour filling over cooled crust. Bake for 45-55 minutes, or until the edges are set and the center jiggles slightly.
Cool in the pan for 1 hour, then chill in the refrigerator for at least 4 hours or overnight.
Remove from pan, slice, and serve.